Andy Lampkins

Andy Lampkins, PhD, 制药D

Interim Dean of the College of Education and Health Sciences
Department Chair / Professor / Physician Assistant Science

Room 3025, Stone Family Center for Health Sciences
812-488-2356
al207@kanaryasevenler.net

Specializations

  • Synthetic Organic 化学istry
  • Drug design/discovery
  • Medicinal 化学istry
  • New Reaction Development
  • 社区 制药acy

度

  • 制药. D. - Butler University
  • PhD - University of Florida

Research Interests

Dr. Andy Lampkins joined the faculty at the University of Evansville in 2013 as the G. Richard and Rita ’59 Eykamp Endowed Chair in 化学istry. Prior to coming to UE, he held positions as a Walther Cancer Institute Postdoctoral Fellow at the University of Notre Dame, and was a faculty member at Samford University. Dr. Lampkins’ research interests span molecular synthesis, new reaction development, and drug design/discovery. Specifically, his group uses organic chemistry as a tool to solve problems in medicine. Current project areas in his laboratories include: 1. the discovery of structurally novel beta-secretase inhibitor prodrugs for the treatment of Alzheimer’s disease, 2. synthesizing biologically-active amino acid-derived natural products using atom-economical multicomponent reactions, 和3. the development of “smart” therapeutics that can target, detect, and treat disease simultaneously.

Selected Publications

  • 罗斯科,M. S., Lampkins,. J.哈珀，S.尼迈耶，G. “Heart Failure: A Dynamic Approach to Classification and Management”, 临床医生牧师. 2018, 28 (5), 32-43.

  • 的价值,. C.; Needham, C. E.; Franklin, D. B.; Lampkins,. J. “Facile Synthesis of Lipophilic d-Amino Acid Conjugates from 4-Alkoxy-Dithionaphthoic Acids”, Synth. Commun., 2012, 42, 2694-2706.

  • 根据J. P.; Evans, Z. M.; Driver, J. A.; Pozzo, E. J.; Lampkins,. J. “Synthesis of Chiral Iodo-N,O-Acetonide Aminal Scaffolds via an Efficient Cascade Reaction of Amino Acid-Derived Epoxides”, Tetrahedron 列托语., 2011, 52, 6908-6910.

  • 史密斯,B. A.; Akers, W. J.; Leevy, W. M.; Lampkins,. J.; Xiao, S.; Wolter, W.; Suckow, M. A.; Achilefu, S.; 史密斯,B. D.”Optical Imaging of Mammary and Prostate Tumors in Living Animals using a Synthetic Near Infrared Zinc(II)-Dipicolylamine Probe for Anionic Cell Surfaces”, J. Am. 化学. Soc. 2010, 132, 67-69.

  • Lampkins,. J.; O’Neil, E. J.; 史密斯,B. D. “Bio-orthogonal Phosphatidylserine Conjugates for Delivery and Imaging Applications”, J. Org. 化学. (Featured Article) 2008, 73, 6053-6058.

  • Lampkins,. J.; Li, Y.; Al-Abbas, A.; Abboud, K. A.; Ghiviriga, I.; Castellano, R. K. “Assessable Consequences of Donor–s–Acceptor Interactions in b-Aminoketones”, 化学. 欧元. J. 2008, 14, 1452-1463.

  • Lampkins,. J.; Abdul-Rahim, O.; Castellano, R. K. “Remote Asymmetric Induction About a Crowded Aromatic Core”, J. Org. 化学. 2006, 71, 5815-5818.

  • Lampkins,. J.; Abdul-Rahim, O.; Li, H.; Castellano, R. K. “Enhanced Small-Molecule Assembly through Directional Intramolecular Forces”, Org. 列托语. 2005, 7, 4471-4474.